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L. interrogans genes encoding known or putative surface proteins selected for binding to endothelial cells.

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_L_interrogans_genes_encoding_known_or_putative_surface_proteins_selected_for_binding_to_endothelial_cells_/1191251
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Phage clones pre-adsorbed on ECM and subjected to three rounds of selection in EA.hy926 cells were analyzed to identify the inserted L. interrogans sv. Copenhageni st. Fiocruz L1–130 gene. Out of the 931 phage clones selected, 779 have L. interrogans DNA inserts that represent 185 unique genes. Thirty-seven of these genes contain signal sequence. Four genes shown below were prioritized for further assessment.*During translocation, the signal sequence of lipoproteins and transmembrane OMPs are cleaved by lipoprotein signal transpeptidase (Lsp) and leader peptidase (Lep), respectively.L. interrogans genes encoding known or putative surface proteins selected for binding to endothelial cells.
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2015-12-02
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