Additional file 1: Table S1. of A compendium of human genes regulating feeding behavior and body weight, its functional characterization and identification of GWAS genes involved in brain-specific PPI network

Human genes (105) controlling feeding behavior that were collected from scientific publications (research papers and review articles); Table S2. Human genes (336) controlling feeding behavior or body weight that were collected from OMIM; Table S3. Human genes (37) associated with syndromes that include obesity as one of the phenotypic characteristics (Bardet-Biedl, Prader-Willi, Alstrom, etc); Table S4. Data from the GWAS meta-analysis papers. Lead SNPs with genome-wide significant (p-value < 5 × 10−8) associations with BMI (164); and genes listed in GWAS meta-analysis articles and located in the regions around the 164 lead SNPs (184). Table S5. All genes from the compendium (578 genes); Table S6. The brain-specific sublist of genes (column C) that was obtained by merging two lists (presented in columns A and B); Table S7. Top twenty genes that have the maximal numbers of the first neighbors in each network (Experimental, Knowledge, Homology) and their main characteristics; Table S8. Unconnected subnetworks found within the network Homology; Table S9. Top-scoring GO terms from the chart GOTERM_BP_5 obtained with the DAVID tool for three lists of genes. The lists of genes analyzed here were obtained by extending three top-scoring clusters revealed in the protein interaction network Experimental with the MCODE tool (see Module network analysis section). Only GO terms with FDR below E-07 are presented; Table S10. Genes from the GWAS meta-analysis set that are involved in three networks (Experimental, Knowledge, Homology) and have at least one neighbor; Table S11. Genes involved in the brain-specific network of PPIs (Section A) and single (isolated) genes (Section B) that belong to the sublist brain-specific. (XLSX 188 kb)