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Targeting Aberrant Replication and DNA Repair Events for Treating Breast Cancers

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE161911
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We aimed to determine carbazole blue's (CB) targets by gene expression microarray. Our results show that CB inhibits the expression of pro-tumorigenic genes that promote unchecked replication and aberrant DNA repair that cancer cells get addicted to survive. Samples collected from CB treated at 2 different doses are comparied to control group for target identifiation. 2 replicates were performed.
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2022-06-02
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