Vaxar

Vaxar is a web-based database and analysis system that stores manually curated data regarding vaccine-induced responses in animals. To date, Vaxar encompasses models from 35 animal species including rodents, rabbits, ferrets, primates, and birds. These 35 species have been used to study more than 1300 experimentally tested vaccines for 164 pathogens and diseases significant to humans and domestic animals.Vaxar can also be used to identify variables that affect responses to different vaccines in a specific animal model. All data stored in Vaxar are publically available for web-based queries and analyses. Overall Vaxar provides a unique systematic approach for understanding vaccine-induced host immunity.Vaxar是一款基于网页的数据库与分析系统，用于存储经人工整理的动物疫苗诱导免疫应答相关数据。截至目前，Vaxar已收录35种动物的研究模型，涵盖啮齿类、兔类、雪貂、灵长类及鸟类等类群。依托这35种动物模型，研究人员已针对164种累及人类与家畜的病原体及疾病，开展了超过1300款经实验验证的疫苗研究。Vaxar还可用于识别特定动物模型中影响不同疫苗应答的变量因素。平台内存储的全部数据均对外开放，支持基于网页的查询与分析操作。总体而言，Vaxar为解析疫苗诱导的宿主免疫应答提供了一套独特的系统性研究范式。