Single-cell immune cell–resolved Mendelian randomization identifies a protective causal role of complement factor D in CD4⁺KLRB1⁻ T cell against small cell lung cancer risk
收藏DataCite Commons2026-05-05 更新2026-05-07 收录
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https://zenodo.org/doi/10.5281/zenodo.19110796
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资源简介：
Supplementary File 1. Paraptosis-related gene set curation and instrument summary (eQTLGen/GTEx/OneK1K).
Supplementary File 2. Full MR screening results and sensitivity diagnostics for the eQTLGen stage.
Supplementary File 3. GTEx v10 whole-blood eQTL exposure data extraction for validation candidates.
Supplementary File 4. GTEx-based instrument construction details.
Supplementary File 5. Validation MR estimates and robustness outputs using GTEx whole-blood instruments.
Supplementary File 6. Differential expression results for CFD (and comparator genes) across four GEO cohorts.
Supplementary File 7. OneK1K PBMC single-cell eQTL exposure files for 14 immune cell types.
Supplementary File 8. Single-cell instrument selection and LD processing per immune cell type.
Supplementary File 9. Immune cell–resolved MR results and sensitivity analyses across immune subsets.
提供机构：
Zenodo
创建时间：
2026-04-16
