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Most existing research uses experimental designs for testing, which cannot efficiently analyse the migration and sorting rules of particles in the disturbed slurry. Therefore, based on the fluidized bed flow film theory, a slurry flow film structure system is established according to the disturbance state of the fluid. On this basis, the particle size and distribution law of the disturbing force formed by slurry disturbance are analyzed, and the calculation model of single particle lift in the flowing film is also analyzed. On this basis, using Markov probability model, the probability of particle lifting and sorting between layers is theoretically deduced. Then, according to the particle ratio of the original mud, the settlement gradation of the particles in the disturbance is analyzed. It can also predict the separation degree of particle in natural turbulence, fluidized beds, and sludge mechanical dewatering. Finally, according to the particle flow software PFC (Particle Flow Code), the main influencing parameters (disturbing force and gradation) were verified and analyzed. The results show that the particle flow simulation results are in good agreement with the calculation results. The model of slurry membrane separation proposed in this paper can provide a basis for studying the mechanism of slurry disturbance separation and particle deposition.