A (−)-Sparteine-Directed Highly Enantioselective Synthesis of Boroproline. Solid- and Solution-State Structure and Properties
收藏NIAID Data Ecosystem2026-03-06 收录
下载链接：
https://figshare.com/articles/dataset/A_Sparteine_Directed_Highly_Enantioselective_Synthesis_of_Boroproline_Solid_and_Solution_State_Structure_and_Properties/2992861
下载链接
链接失效反馈官方服务：
资源简介：
A two-step, direct asymmetric synthesis of the trifluoroacetate ammonium salt of boroproline is reported. (−)-Sparteine-mediated lithiation of N-Boc-pyrrolidine afforded
N-Boc-aminoboronic acid in good yield and enantioselectivity as determined by HPLC (pinanediol ester). Deprotection using TFA yielded the ammonium salt; full characterization data are presented, and the structure in aqueous
solution and the occurrence of a B−N species are discussed.
创建时间：
2016-02-28
