Changes of intestinal flora in cholestatic liver disease and the changes after JTE-013 intervention

We investigated the microflora changes in cholestatic liver disease and the changes in intestinal microflora induced by S1PR2 inhibitors. We used CBDL model to explore the changes of microflora, and divided the rats into 3 groups, sham group, CBDL group and JTE-013 group to explore the changes of microflora in the three groups.