Significant positive selection results in a minimum of two different tests.

Observed (Obs) FST with selection significance (highlighted P value<0.01) for the three continents (Africa, Asia and Europe) and for Europe and North Africa. Global cross-continental FST scores in the CEU, CHB, and YRI samples from the 1000 Genomes Selection Browser. Significant high and low FST values (extreme top 5% values of the distribution of FST values across the genome) are highlighted in bold. P values were calculated on the basis of higher rank scores in the genomic distribution. SPA scores for continental European, and North African allele gradients (highlighted in bold SPA scores above 99th percentile).