Summary of the impact of different software settings on LCI of N₂MBW.

Overview of impact on LCI after change of software settings. High quality N2MBW tests of 30 children with different lung disease were reanalyzed with changed software settings. Several parameters were changed according to four sectors, environmental conditions (e.g. ambient temperature), setup parameter (apparatus dead space), software algorithm (e.g. O2 response-time correction), and flow-gas signal delay times. Because of the uniformity of change statistical significance might be reached over the study population without clinical relevance (defined as >10% change of baseline LCI for the individual measurement; and for the change in software setting if >10% of all children showed such a LCI change >10%). Summary of the impact of different software settings on LCI of N2MBW.