(A) Whole-cell recordings of KCa3.1 in murine 3T3 fibroblasts. KCa3.1 currents were pre-activated by infusion of 1 μM Ca2+ via the patch-pipette as previously described [38]. Pre-activated currents (c
In 1972, J. Woodland Hastings and colleagues predicted the existence of a proton selective channel (HV1) that opens in response to depolarizing voltage across the vacuole membrane of bioluminescent di
