We determined the actively translated mRNA induced/repressed by a Dietary Restriction intervention specifically in the differentiated enterocytes of the intestine. For this, we did a "genetic dissecti

NIAID Data Ecosystem30

CX DHPG TRAP-seq

海马突触可塑性

翻译组学

Sequencing files from TRAP-seq samples isolated from DHPG-stimulated WT and Fmr1-/y hippocampal slices incubated with vehicle or 200 nM CX-5461 Hippocampal slices were prepared from 4 littermate pair

NIAID Data Ecosystem20

Resolving Chromosome-Centric Human Proteome with Translating mRNA Analysis: A Strategic Demonstration

染色体中心蛋白质组学

翻译组学

Chromosome-centric human proteome project (C-HPP) aims at differentiating chromosome-based and tissue-specific protein compositions in terms of protein expression, quantification, and modification. We

NIAID Data Ecosystem30

IFN-γ-induced iNOS expression in regulatory macrophages prolongs allograft graft survival in fully immunocompetent recipients.

移植免疫调节

巨噬细胞免疫

Mouse monocytes exposed to M-CSF and IFN-γ were driven to a suppressor phenotype over a seven day culture period. The resulting regulatory macrophages (M regs) expressed markers distinguishing them fr

NIAID Data Ecosystem20

Genome-wide translational analysis of RAW264 macrophages by ribosome profiling

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