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Cryo-EM dataset of 80S ribosomes from yeast

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IEEE2026-04-17 收录
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https://ieee-dataport.org/documents/cryo-em-dataset-80s-ribosomes-yeast
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Cryo-EM dataset of 80S ribosomes from yeast. This dataset has been described in Dashti et al. (2014, PNAS) Trajectories of the ribosome as a Brownian nanomachine. In that study, a subset of the dataset was used to demonstrate the performance of a machine learning technique (now termed ManifoldEM) using manifold embedding to determine the energy landscape of a molecule. The dataset is re-analyzed in Seitz et al. (2022, IEEE TCI) Recovery of conformational continuum from single-particle cryo-EM images: Optimization of ManifoldEM informed by ground truth to assess improvements of a new method with respect to the original 2014 study. 
提供机构:
Pallesen, Jesper; Simon, Ann; Meskauskas, Arturas; Stupina, Vera; Dinman, Jonathan; Frank, Joachim; Sharma, Gyanesh
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