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Transcriptional impact of conditional loss of Notch2 from adult NSCs. Mus musculus

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下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA390080
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资源简介:
Adult NSCs maintenance depends on intakt Notch signaling. The role of Notch2 has only been marginally studied in adult neurogenesis. To adress the role of the Notch2 paralogue we conditionally deleted Notch2 from the adult SVZ and analysed the Notch2-deficient cells at distinct time points. Overall design: Loss of Notch2 was conditionally induced in adult, Notch2 floxed mice. Recombined cells were sorted and processed ex vivo. We used microarrays to detail transcriptional changes upon gene deletion.
创建时间:
2017-06-12
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