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Crystal structure of cruzain covalently bound to a purine nitrile

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Crystal structure of cruzain covalently bound to a purine nitrile Descriptor: 6-[(3,5-difluorophenyl)amino]-9-ethyl-9H-purine-2-carbonitrile, Cruzipain Authors: Ferreira, R.S, Shoichet, B.K, McKerrow, J.H. Deposit date: 2009-06-24 Release date: 2009-12-15 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Identification and optimization of inhibitors of trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB. J.Med.Chem., 53, 2010
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2009-06-24
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