Transcription profiling of mouse SAP102 and PSD-95 knockouts compared to their wild-type littermates

ChEBI2007-09-01 更新2026-07-21 收录

突触蛋白功能

神经发育障碍分子机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MEXP-1159 数据链接链接失效反馈

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资源简介：

Transcription profiling of mouse SAP102 and PSD-95 knockouts compared to their wild-type littermates

创建时间：

2007-09-01

Additional file 5: of Effects of a social stimulus on gene expression in a mouse model of fragile X syndrome

神经发育障碍分子机制

脆性X综合征基因表达

Overlapping genes of comparisons in each brain region. The differentially expressed genes (DEGs) that overlapped in specific comparisons are listed. The first column indicates DEGs significantly regul

NIAID Data Ecosystem80

FOXG1 and DDX5 control PRKAR2B expression via miR200 in a mouse model of atypical Rett-syndrome

神经发育障碍分子机制

miRNA生物合成调控

Rett syndrome is a complex neurodevelopmental disorder that is mainly caused by mutations in MECP2. However, mutations in FOXG1 cause a less frequent non-congenital form called atypical Rett syndrome.

NIAID Data Ecosystem50

Synaptic_Based_灵长类皮质间通信突触组织研究数据

突触蛋白功能

感知信息处理

本数据集聚焦灵长类体感皮质区域3b和1的突触组织，通过顺行追踪与三维电镜重建，研究内区域和区域间投射中大小突触 bouton 的分布、结构特征及功能差异，验证大 bouton 的驱动样功能，支持触觉信息快速传播机制的结论。

海数据30

Molecular pathogenesis of several neurodevelopmental disorders converges on MeCP2-TCF20 complex interactions

神经发育障碍分子机制

MeCP2蛋白

Neurodevelopmental disorders (NDDs) are genetically heterogeneous, yet often share certain features such as intellectual disability or motor incoordination. MeCP2 dysfunction is associated with MECP2

NIAID Data Ecosystem60

Prefrontal cortex transcriptome of Arid1b heterozygote mutantation mice and drug treated-mice age of postnatal day 120. Prefrontal cortex transcriptome of Arid1b heterozygote mutantation mice and drug treated-mice age of postnatal day 120

神经发育障碍分子机制

药物诱导转录组重编程

Arid1b is a chromatin remodeler implicated in neurodevelopmental disorders. Arid1b mutant mice with haploinsufficiency (Arid1b HT) displayed persistent excitatory synaptic dysfunction from juvenile to

NIAID Data Ecosystem40

Transcription profiling of mouse SAP102 and PSD-95 knockouts compared to their wild-type littermates

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