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IRAK4 in complex with Compound 28

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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IRAK4 in complex with Compound 28 Descriptor: Interleukin-1 receptor-associated kinase 4, ~{N}-(4-morpholin-4-ylcyclohexyl)-5-(oxan-4-yl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine Authors: Ferguson, A.D. Deposit date: 2016-05-25 Release date: 2017-12-06 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.74 Å) Cite: Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265P Diffuse Large B-Cell Lymphoma. J. Med. Chem., 60, 2017
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2016-05-25
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