Structure of phospholipase D BetaIB1i from Sicarius terrosus venom, H47N mutant bound to substrate sphingolipids at 2.60 A resolution

Structure of phospholipase D BetaIB1i from Sicarius terrosus venom, H47N mutant bound to substrate sphingolipids at 2.60 A resolution Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-aminoethyl (2S,3R,4E)-2-dodecanamido-3-hydroxyheptadec-4-en-1-yl hydrogen (S)-phosphate, Dermonecrotic toxin StSicTox-betaIB1i, ... Authors: Sundman, A.K, Montfort, W.R, Binford, G.J, Cordes, M.H. Deposit date: 2025-06-05 Release date: 2025-12-03 Last modified: 2026-06-24 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Spider venom phospholipase D toxin structure: Interfacial binding site, mechanism, activation, and head group preference. Proc.Natl.Acad.Sci.USA, 123, 2026