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Crystal Structure of FGFR4 with an Irreversible Inhibitor

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal Structure of FGFR4 with an Irreversible Inhibitor Descriptor: Fibroblast growth factor receptor 4, N-(2-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}-3-methylphenyl)propanamide, SULFATE ION Authors: Kim, J.L, Miduturu, C, Hodous, B, Brooijmans, N, Bifulco, N, Guzi, T. Deposit date: 2014-12-18 Release date: 2015-04-01 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.71 Å) Cite: First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway. Cancer Discov, 5, 2015
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2014-12-18
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