Changes in different characteristics of the yeast V H+- ATPase by extracellular glucose according to the current mechanistic model and experimental data of this study*.

*All changes in characteristics for activated enzyme state are related to the respective characteristics for its non-activated state taken as one unit.**Increase predicted by model. The ratio of the specific enzyme activities of vacuole membranes is used when non-activated enzyme has 1.5 units/mg (38.5% of the activated enzyme) [18], since Vmax for two enzyme states are not available in literature. That corresponds to the increase for V max of activated enzyme and the immune reactivity and protein content of subunits A and B by 2.6 folds, when the conformational changes and epitopes availability are not modified by glucose according to the current model. The contradictions between experimental data and the predictions of the mechanistic model are in bold.