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Natural transformation is dependent on cAMP, which is produced by adenylate cyclase (CyaA) and degraded by cAMP-degrading phosphodiesterase (CpdA).

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https://figshare.com/articles/dataset/_Natural_transformation_is_dependent_on_cAMP_which_is_produced_by_adenylate_cyclase_CyaA_and_degraded_by_cAMP_degrading_phosphodiesterase_CpdA_/290763
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#Competence was induced by the addition of 0.02% arabinose wherever indicated. * Statistically significant difference in comparison to the wild type strain A1552-TntfoX; P<0.05; Average of at least three independent experiments.
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2012-06-21
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