拉萨藏族人群Y染色体SNP及STR分型数据

为研究拉萨藏族人群的复习遗传结构，我们采集了1029个拉萨藏族个体。首先，通过SNP分型的方法，确定了每个样本的单倍群归属。其次，采用ABI 3130XL，用荧光标记引物对8个STR进行了检测，以进一步研究该人群的Y染色体遗传多样性。结果表明，拉萨藏族人群中的D-M174频率最高（56.56%，其中D3*-P99最多），其次是O-M175 (30.71%，主要以O3a3c1-M117为主。此外，还有一些低频的类群，如N-M231(5.15%，主要是N1*-LLY22)，C-M130 (2.62%)、R-M207 (2.53%)、Q (1.55%)、J (0.68%)、K-M以及T。进一步分析表明，拉萨藏族人群的Y染色体组分存在时间上的分层，包括3万年前、末次盛冰期、末次盛冰期后、全新世等时期，反映了不同时期的定居历史。To investigate the population genetic structure of the Lhasa Tibetan population, we collected 1029 Lhasa Tibetan individuals as research samples. First, we determined the haplogroup assignment of each sample via SNP genotyping. Second, we detected 8 STR loci using fluorescence-labeled primers on an ABI 3130XL genetic analyzer to further explore the Y-chromosomal genetic diversity of this population. The results showed that haplogroup D-M174 had the highest frequency in the Lhasa Tibetan population (56.56%, with D3*-P99 being the most prevalent subtype), followed by O-M175 (30.71%, mainly represented by O3a3c1-M117). In addition, there were several low-frequency haplogroups, including N-M231 (5.15%, mostly N1*-LLY22), C-M130 (2.62%), R-M207 (2.53%), Q (1.55%), J (0.68%), K-M, and T. Further analysis revealed temporal stratification in the Y-chromosomal component of the Lhasa Tibetan population, dating to approximately 30,000 years ago, the Last Glacial Maximum (LGM), post-LGM, and the Holocene, which reflects the settlement history across different periods.

搜集汇总

背景与挑战

背景概述

该数据集包含拉萨藏族人群的Y染色体遗传数据，通过SNP和STR分型分析1029个个体，揭示了D-M174和O-M175为主要单倍群，并反映了不同历史时期的定居分层。数据以xls格式存储，适用于遗传结构研究，并需引用指定文献和资助项目。