Factor XIa in Complex with Compound 2k
收藏Protein Data Bank Japan2024-10-09 更新2026-03-28 收录
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Factor XIa in Complex with Compound 2k Descriptor: 5-[3-chloranyl-2-fluoranyl-6-(1,2,3,4-tetrazol-1-yl)phenyl]-2-[(1~{R})-2-cyclopropyl-1-[4-(3-methylimidazol-4-yl)pyrazol-1-yl]ethyl]-1-oxidanyl-pyridine, CITRIC ACID, Coagulation factor XIa light chain Authors: Shaffer, P.L, Milligan, C.M, Cedervall, P. Deposit date: 2022-05-11 Release date: 2022-08-03 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.522 Å) Cite: Discovery of Potent and Orally Bioavailable Pyridine N-Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions. J.Med.Chem., 65, 2022
创建时间：
2022-05-11
