Interleukin 6 (IL-6) is a pleiotropic cytokine with diverse roles in homeostasis, inflammation, and cancer. Here we performed transcriptional profiling of OT-I CD8+ T cells activated in the presence o

NIAID Data Ecosystem40

Table_4_A Mechanistic Computational Model Reveals That Plasticity of CD4+ T Cell Differentiation Is a Function of Cytokine Composition and Dosage.XLSX

T细胞分化可塑性建模

细胞信号调控

CD4+ T cells provide cell-mediated immunity in response to various antigens. During an immune response, naïve CD4+ T cells differentiate into specialized effector T helper (Th1, Th2, and Th17) cells a

NIAID Data Ecosystem30

comparison_cul4_as_dark_light-Functional analysis of the SKP2 and CUL4 proteins

蛋白质功能分析

细胞信号调控

comparison_cul4_as_dark_light-Functional analysis of the SKP2 and CUL4 proteins

ChEBI2012-03-26 更新40

The Human Cytomegalovirus UL11 Protein Interacts with the Receptor Tyrosine Phosphatase CD45, Resulting in Functional Paralysis of T Cells

病毒免疫逃逸机制

细胞信号调控

Human cytomegalovirus (CMV) exerts diverse and complex effects on the immune system, not all of which have been attributed to viral genes. Acute CMV infection results in transient restrictions in T ce

NIAID Data Ecosystem40

Regulating Interleukin-2 activity with engineered receptor signaling clamps

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