An epigenetic single-cell atlas of IDH-mutant glioma reveals the role of ATRX in shaping tumor composition
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https://www.omicsdi.org/dataset/ega/EGAS00001004523
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Recent single-cell RNA-sequencing studies have identified a hierarchy of cell types that is common to all isocitrate dehydrogenase (IDH) -mutant gliomas. This finding is somewhat paradoxical since the genetic differences between IDH-mutant astrocytomas and IDH-mutant oligodendrogliomas are prognostic, predictive of therapeutic response, and correlated with differences in immune infiltrates. To integrate these disparate findings, we constructed a single-cell atlas of 28 human IDH-mutant primary untreated grade-II/III gliomas.EGA study EGAS00001004523
创建时间：
2021-10-28
