Gene expression profile in 7.5ED embryos, 14.5ED embryos and liver of 7.5 neonates from either control or obese (SL) grandfathers

We developed a mouse model of childhood obesity. We next explored whether the effects of childhood obesity influence patterns of expression on the grandoffspring. The main objective of this study is to find differentially expressed genes in samples of embryos or liver of early post-natal mice derived from obese parents as opposed to the progeny derived from non-obese (control) parental mice. We collected and analyzed the expression profileof embryos (ED7,5; ED14,5) and noenatal liver (PN7.5) in the grandoffpring of control and obese mice.