Expression data from gastric cancer cell line SGC-7901. Expression data from gastric cancer cell line SGC-7901

miR-375 plays an irreplaceable role in regulation of neoplastic progression in gastric cancer. In order to study the mechanism by which miR-375 inhibits the stemness of gastric cancer cell lines, we need to explore the genetic program controlled by miR-375. We used microarrays to detail the global program of gene expression underlying miR-375 up-regulation and identified distinct classes of regulated genes during this process. Overall design: A miR-375 stably overexpressing gastric cancer cell line was constructed by lentivirus infection for RNA extraction and hybridization on Affymetrix microarray. The experimental group and the control group were repeated three times each.