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I<sub>2</sub>‑Catalyzed Oxidative Coupling Reactions of Hydrazones and Amines and the Application in the Synthesis of 1,3,5-Trisubstituted 1,2,4-Triazoles

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NIAID Data Ecosystem2026-03-09 收录
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A general and expeditious approach for the metal-free mediated synthesis of 1,3,5-trisubstituted 1,2,4-triazoles from hydrazones and aliphatic amines has been achieved under aerobic oxidative conditions. The reaction proceeds through a cascade C–H functionalization, double C–N bonds formation, and oxidative aromatization sequence.

创建时间:
2016-03-14
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