Clinicopathological features of 19 DLBCL with a serum monoclonal IgM protein.

CNS1: Central nervous system involvement at diagnosis or during relapse progression.COO2: Cell of Origin defined by the Hans algorithm.IgM-I3: heavy chain IgM expression assessed by immunohistochemistry.MYC-I4: MYC protein expression by immunohistochemistry.BCL2-I5: BCL2 protein expression by immunohistochemistry.MYC-f6: MYC gene translocation by FISH analysis.BCL2-f7: BCL2 gene translocation by FISH analysis, carried out by both IGH/BCL2 and BCL2 break apart probes.BCL6-f8: BCL6 gene translocation by FISH analysis.MYD889: MYD88 gene analyzed for L265P mutation.FUP10: Follow-up.NE11: Not evaluable.NT12: Not translocated.T13: Translocated.CCR114:1st Continuous complete remission.CCR215: 2nd Continuous complete remission.WT16: wild type.