five

Crystal Structure of Anaplastic Lymphoma Kinase (ALK) in complex with 5a

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Protein Data Bank Japan2024-03-20 更新2026-03-21 收录
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Crystal Structure of Anaplastic Lymphoma Kinase (ALK) in complex with 5a Descriptor: ALK tyrosine kinase receptor, N-[3-(4-{[(5-tert-butyl-1,2-oxazol-3-yl)carbamoyl]amino}-3-methylphenyl)-1H-pyrazol-5-yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide Authors: Tu, C.H, Wu, S.Y. Deposit date: 2016-03-18 Release date: 2016-05-18 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Pyrazolylamine Derivatives Reveal the Conformational Switching between Type I and Type II Binding Modes of Anaplastic Lymphoma Kinase (ALK). J.Med.Chem., 59, 2016
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2016-03-18
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