RNA sequencing of preB-ALL NALM-6 cells with or without XIAP-knockdown, using prime-seq
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE184011
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资源简介：
In this study we performed molecular manipulation of XIAP in vivo using microRNA-30 flanked shRNA expression in cell lines models of r/r ALL. Interestingly, upon strong XIAP knockdown, r/r ALL cells were outcompeted in vivo, while intermediate knockdown sensitized cells to chemotherapy. Using prime-seq we wanted to characterized NALM-6 cells expressing different XIAP levels. XIAP KD and control NALM-6 cells were isolated out of the murine bone marrow at different time points. the mRNA expression pattern was analyzed. NOTE FROM SUBMITTER: Due to legal regulations in Germany, we are not allowed to publish raw sequencing data. We already asked for permission to only publish the raw counts.
创建时间：
2023-01-10
