Table 1 in Bioengineering of an elastase inhibitor from Caesalpinia echinata (Brazil wood) seeds

Table 1 Inhibition constants (Ki) of recombinant protease inhibitors for different serine proteases.
EnzymeSubstrateKi (nM)CeEI*rCeEI-rCeEI-54**Human neutrophilMeO-Suc-Ala-Ala-3.55 ±0.67 ±0.57 ±elastasePro-Val-pNan2.330.050.32Human cathepsin GSuc-Ala-Ala-Pro-5.07 ±6.54 ±90.4 ±Phe-pNAn2.080.1153.1Human plasmaH-D-Pro-Phe-Arg-0.10 ±1.00 ±2.73 ±kallikreinpNan0.010.081.13BovineSuc-Phe-pNan117 ± 827.6 ±108 ±49chymotrypsin5.1Bovine trypsinH-D-Pro-Phe-Arg-n.i.50 ± 1200 ±29pNanBacterial subtilisin ABoc-Gly-Gly-Leu-notn.i.n.i.pNantestedHuman tissueH-D-Val-Leu-Lys-n.i.n.i.n.i.kallikrein 1pNan
Data are presented as means ± standard error (SEM) of three individual experiments in duplicates.
*[Cruz-Silva et al., 2013], **[Cruz-Silva et al., 2016].
n.i. not inhibited.