Crystal structure of the human CDKL5 kinase domain with compound YL-354
收藏Protein Data Bank Japan2024-03-27 更新2026-04-25 收录
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资源简介：
Crystal structure of the human CDKL5 kinase domain with compound YL-354 Descriptor: 4-[[3,5-bis(fluoranyl)phenyl]carbonylamino]-~{N}-piperidin-4-yl-1~{H}-pyrazole-3-carboxamide, Cyclin-dependent kinase-like 5, SULFATE ION Authors: Richardson, W, Chen, X, Newman, J.A, Bakshi, S, Lakshminarayana, B, Brooke, L, Bullock, A.N. Deposit date: 2023-02-09 Release date: 2023-06-14 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. Acs Chem Neurosci, 14, 2023
创建时间：
2023-02-09
