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Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-(1-o-carboranylmethyl)-6-methylpyrimidine, A novel boron containing, nonclassical Antifolate

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Protein Data Bank Japan2024-05-01 更新2026-03-21 收录
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Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-(1-o-carboranylmethyl)-6-methylpyrimidine, A novel boron containing, nonclassical Antifolate Descriptor: 2,4-DIAMINO-5-(1-O-CARBORANYLMETHYL)-6-METHYLPYRIMIDINE, DIHYDROFOLATE REDUCTASE, GLYCEROL, ... Authors: Leung, A.K.W, Reynolds, R.C, Riordan, J.M, Borhani, D.W. Deposit date: 2005-09-29 Release date: 2007-04-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Novel Boron-Containing, Nonclassical Antifolates: Synthesis and Preliminary Biological and Structural Evaluation. J.Med.Chem., 50, 2007
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2005-09-29
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