Bovine Glycomacropeptide promotes the growth of Bifidobacterium longum subsp. infantis and modulates its gene expression. Bifidobacterium longum subsp. infantis

Microarray analysis of gene transcription in B. infantis following exposure to Glycomacropeptide (GMP) revealed a substantial transcriptional response to GMP relative to untreated bacteria or bacteria treated with periodate denatured GMP-P, with a greater number of differentially expressed transcripts and larger fold changes versus the control. The pool of differentially expressed transcripts included two glycoside hydrolase (family 25) genes, which were substantially up-regulated following exposure to GMP but not GMP-P. Overall design: 9 samples were analysed comprising 3 biological replicates for each of 3 treatment conditions