New Chiral Benzothiazine Ligand and Its Use in the Synthesis of a Chiral Receptor

The development of chiral ligands to direct the course and
stereoselectivity of many catalytic asymmetric reactions is
an important area of interest for many research groups. As
part of a program examining the chemistry of 2,1-benzothiazines, we have prepared a new chiral benzothiazine
ligand. This ligand can be made in as few as three steps
from commercially available starting materials. Presented
herein is the synthesis of the ligand along with the synthesis
of a chiral molecular receptor that potentially presages a new
class of chiral molecular tweezers.