Additional file 1: Tables S1-S6. of Placental methylome analysis from a prospective autism study

Table S1. MethylC-seq sequencing statistics. Table S2. Average methylation over all PMDs and HMDs in placental samples. Table S3. Average DNA methylation for all chromosomes in placental samples. Table also shows average methylation over all autosomes, which is the average methylation over all CpG sites in the autosomes, not just the average over the chromosome-wide averages. Table S4. Average autosomal DNA methylation for ChromHMM states in placental samples. For each ChromHMM state and each placental sample, average methylation was calculated for all autosomal CpG sites in elements of that state. Table S5. Pyrosequencing analysis at the DLL1 locus. Percent methylation for each of the 3 CpG sites (P1, P2, P3) was determined by pyrosequencing for each ASD, TD, and ODC placental sample. Table S6. Demographic and environmental factors in relation to placental methylation. Statistical analyses of potential covariates including, run, order, coverage, ethnicity, and sex with methylation of PMD, HMD, % 20Â kb windows <60% methylation, and DLL1 locus. (XLSX 51 kb)