Grk6

Predicted to enable G protein-coupled receptor kinase activity and beta-adrenergic receptor kinase activity. Predicted to be involved in desensitization of G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including genitourinary system; liver; lung; spleen; and submandibular gland primordium. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human GRK6 (G protein-coupled receptor kinase 6). [provided by Alliance of Genome Resources, Nov 2024]

预测可激活G蛋白偶联受体激酶活性和β-肾上腺素受体激酶活性。预测参与G蛋白偶联受体信号通路的脱敏作用。预测定位于细胞膜。预测在细胞质中活性。在多个结构中表达，包括泌尿生殖系统、肝脏、肺、脾脏以及下颌下腺原基。此基因的人类同源基因与帕金森病相关。与人类GRK6（G蛋白偶联受体激酶6）同源。[由基因组资源联盟提供，2024年11月]