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Expression data from mice lacking SIRT3 under dietary stress. Mus musculus

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA144471
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SIRT3 is a mitochondrial NAD(+)-dependent protein deacetylase, which regulates the enzymatic activity of several mitochondrial proteins. We used microarrays to identify the differences in gene expression as a result of loss of SIRT3, under standard and high-fat diet conditions Overall design: Wild-type and SIRT3KO mice were sacrificed at 12weeks of age and RNA was extracted from liver tissue, and hybridized on Affymetrix microarrays, to determine differences in gene expression as a result of diet
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2011-07-11
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