官方服务：
资源简介：
Fah mice treated with ABE for 1 month and check the positive Fah coverage
应用场景：
创建时间：
2019-01-04
相关数据集
Modelling, Optimization and Comparable Efficacy of T cells and HSC Gene Editing for treating HIGM1
Precise correction of the CD40LG gene in T cells and hematopoietic stem/progenitor cells (HSPC) holds promise for treating X-linked hyper-IgM Syndrome (HIGM1), but its actual therapeutic potential rem
NIAID Data Ecosystem20
Precise correction of heterozygous SHOX2 mutations in hiPSCs derived from patients with atrial fibrillation via genome editing and sib-selection
Patient-specific human induced pluripotent stem cells (hiPSCs) offer unprecedented opportunities for the investigation of multigenic disease, personalized medicine, and stem cell therapy. For heteroge
NIAID Data Ecosystem20
Indel rate analysis:Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy. Indel rate analysis:Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy
A missense mutation of collagen type VIII alpha 2 chain (COL8A2) gene leads to early onset Fuchs’ endothelial corneal dystrophy (FECD), which can cause blindness through progressive loss of corneal en
NIAID Data Ecosystem10
Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice. Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
NIAID Data Ecosystem20
PAM-Flexible Genome Editing with an Engineered Chimeric Cas9
CRISPR enzymes require a defined protospacer adjacent motif (PAM) flanking a guide RNA-programmed target site, limiting their sequence accessibility for robust genome editing applications. In this stu
NIAID Data Ecosystem10
