Crystal structure of a genotype 1a/3a chimeric HCV NS3/4A protease in complex with danoprevir
收藏Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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Crystal structure of a genotype 1a/3a chimeric HCV NS3/4A protease in complex with danoprevir Descriptor: (2R,6S,12Z,13aS,14aR,16aS)-6-[(tert-butoxycarbonyl)amino]-14a-[(cyclopropylsulfonyl)carbamoyl]-5,16-dioxo-1,2,3,5,6,7,8 ,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 4-fluoro-2H-isoindole-2-carboxylate, NS3 protease, SULFATE ION, ... Authors: Soumana, D, Yilmaz, N.K, Ali, A, Prachanronarong, K.L, Schiffer, C.A. Deposit date: 2015-11-13 Release date: 2016-11-23 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Molecular and Dynamic Mechanism Underlying Drug Resistance in Genotype 3 Hepatitis C NS3/4A Protease. J.Am.Chem.Soc., 138, 2016
创建时间：
2015-11-13
