Expression data from human embryonic kidney 293 (HEK-293) cells transiently transfected with Human endogenous retrovirus (HERV) (K-HML2) Rec protein compared to empty expression vector control

HERV-K protein Rec functions as RNA transport protein shuttling unspliced viral genomic RNA from the nucleus to the cytoplasm. Rec was found to be expressed in several tumors and transformed cell lines and contributes to cell transformation by inhibiting the transcription factor Promyelocytic Leukemia Zinc Finger Protein HEK-293 cells were transfected with Rec expression plasmid or empty vector control (in duplicates). Samples were collected 72h post transfection. Microarray hybridization was carried out at Atlas Biolaps GmbH Berlin according to manufactures protocol. Microarray data was analyzed using Bioconductor. Comparison of Rec expressing cells vs. Rec non-expressing cells.