Attentional modulation of secondary somatosensory and visual thalamus of mice

Each sensory modality has its own primary and secondary thalamic nuclei. While the primary thalamic nuclei are well understood to relay sensory information from the periphery to the cortex, the role of secondary sensory nuclei is elusive. One hypothesis has been that secondary nuclei may support feature-based attention. If this is true, one would also expect the activity in different nuclei to reflect the degree to which modalities are or are not behaviorally relevant in a task. We trained head-fixed mice to attend to one sensory modality while ignoring a second modality, namely to attend to touch and ignore vision, or vice versa. Arrays were used to record simultaneously from secondary somatosensory thalamus (POm) and secondary visual thalamus (LP). In mice trained to respond to tactile stimuli and ignore visual stimuli, POm was robustly activated by touch and largely unresponsive to visual stimuli. A different pattern was observed when mice were trained to respond to visual stimuli an..., Electrophysiology and behavior data was acquired with OpenEphys. Electrophysiology data was preprocessed with Kilosort3 and Phy. Behavior data was preprocessed with custom MATLAB software. , , # Data from: Attentional modulation of secondary somatosensory and visual thalamus of mice

[https://doi.org/10.5061/dryad.4j0zpc8n0](https://doi.org/10.5061/dryad.4j0zpc8n0)

## Description of the data and file structure

This dataset is comprised of three MATLAB .mat files:

\- ConditioningLearningCurveData.mat

\- RecordingDayBehaviorData.mat

\- RecordingDayNeuralData.mat

**1) ConditioningLearningCurveData.mat**

Measurements of performance on a conditioning task where mice were trained to associate visual or tactile stimuli with a water reward.

This file contains a 23x9 table titled \"LearningCurveTable.\" Each row corresponds to a single mouse. The table has the following fields:

\- MouseID: The unique identifier for each mouse.

\- ExperimentType: The type of task the mouse was conditioned on, either \"Visual\" or \"Tactile\"

\- Sex: Animal sex (M: male | F: female)

\- nSessions: The number of sessions a mouse was conditioned on, including the final day of conditioning when neura...