PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 72
收藏Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 72 Descriptor: (1S,2R,3aR,4S,6aR)-4-[(2-amino-3,5-difluoroquinolin-7-yl)methyl]-2-(4-amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)hexahydropentalene-1,6a(1H)-diol, 1,2-ETHANEDIOL, Methylosome protein 50, ... Authors: Palte, R.L. Deposit date: 2020-10-23 Release date: 2021-04-21 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. J.Med.Chem., 64, 2021
创建时间：
2020-10-23
