Data to produce the results of the publication: “Examining the Role of Intrinsic and Reflexive Contributions to Ankle Joint Hyper-Resistance Treated with Botulinum Toxin-A”

The work distinguishes the contribution of intrinsic and reflexive ankle joint resistance for participants treated with BoNT-A injections to reduce spasticity. <br> In short, we only observed the expected joint resistance reduction due to BoNT-A injections in the MAS (overall resistance). This observed reduction could not be attributed to an unambiguous group-level reduction of the reflexive resistance contribution, as no instrumented measure confirmed the hypothesis. Validity of the instrumented measures was supported through a strong association between different assessment methods.

本研究区分了接受A型肉毒杆菌毒素（BoNT-A）注射以降低踝关节肌痉挛的受试者的踝关节固有阻力与反射性阻力的贡献占比。简言之，我们仅在改良Ashworth量表（MAS，对应整体关节阻力）中观测到了A型肉毒杆菌毒素注射所带来的预期关节阻力降低效果。但该观测到的阻力降低无法归因于反射性阻力贡献在组水平上出现了明确的降低，因为尚无仪器化测量手段能够验证这一假设。不同评估方法间存在较强相关性，这为该仪器化测量手段的效度提供了支撑。