Uncovering Modifier Genes of X-linked Alport Syndrome Using a Novel Multi-parent Mouse Model

RNAseq of mouse kidney RNA from Col4a5 muntant mice crossed with diversity outbred mice to find modifier genes of Alport disease. 192 kidney RNA samples one male and one female sibling pair carrying col4a5 mutation from each DO male used in a col5a4x DO cross本数据集针对Col4a5突变小鼠与多样性远交（DO）系小鼠杂交所得的小鼠肾脏RNA开展RNA测序（RNA-seq），旨在挖掘阿尔波特病（Alport disease）的修饰基因（modifier genes）。实验共包含192份肾脏RNA样本，每一只参与Col5a4x DO杂交的DO雄性小鼠，均对应一对携带Col4a5突变的同胞对（一雄一雌）。