Phase II Study of S-1 plus LV (1 week on and 1 week off) as First-line Treatment for Patients with metastatic colorectal cancer.

Intervention name : S-1 (tegafur + gimeracil + oteracil potassium)
INN of the intervention : S-1: tegafur, gimeracil, oteracil potassium
Dosage And administration of the intervention : S-1 40-60 mg x 2/day was administered orally for one week followed by one week rest.
Intervention name : LV (Levofolinate calcium)
INN of the intervention : folic acid
Dosage And administration of the intervention : LV 25 mg x 2/day was administered orally for one week along with S-1 followed by one week rest.
Primary outcome(s): Efficacy, Safety
Study Design: Open-label, Multi-center Study