BIOGRID CURATED DATA FOR HAL5 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for HAL5 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication

蛋白质-蛋白质、遗传以及化学相互作用数据集针对 HAL5（酿酒酵母 S288c）由 BioGRID（https://thebiogrid.org）精心编纂；定义：疑似蛋白激酶；过表达可增强钠和锂的耐受性，而基因敲除则增加阳离子和低pH的敏感性并损害钾的吸收，暗示其在 Trk1p 和/或 Trk2p 运输蛋白的调节中发挥重要作用；HAL5 存在一种同源蛋白 KKQ8，该同源蛋白由全基因组倍增产生。