A Test Dataset for Open Chrono-Morph Viewer (OCMV)

Open Chrono-Morph Viewer (OCMV) is an open-source image visualization and animation platform handling volumetric time series, especially those containing unequally sampled volumes, such as those produced by 4D (3D+time) cardiac alignment. OCMV is available at https://github.com/ShangWangLab/OpenChronoMorphViewer. This dataset is for demonstrating OCMV’s unique timeline features. It shows the dynamics of the embryonic mouse heart around embryonic day 8.5, consisting of 150 NRRD volumes spanning two timescales. The fast timescale represents the heartbeat phase over the complete cardiac cycle, while the slow timescale represents the development at three timepoints spanning two hours. Across the three developmental timepoints, the number of volumes sampling the heartbeat changes, as does the volume size (number of voxels). The data have two channels: the first channel represents the tissue structure, and the second channel represents the blood flow velocity component along the vertical axis spanning ±9.8 mm/s. The acquisition and processing of this dataset followed the methods described in https://doi.org/10.1364/BOE.475027. All animal manipulations were approved by the Institutional Animal Care and Use Committee at Baylor College of Medicine, and the experiments followed the approved procedures and guidelines.

Acknowledgement: We thank Dr. Irina V. Larina (Baylor College of Medicine) for her support with the experiment.