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Cryo-EM structure of human VMAT2 in presence of Tetrabenazine, determined in an outward-facing conformation

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Protein Data Bank Japan2025-07-02 更新2026-04-19 收录
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Cryo-EM structure of human VMAT2 in presence of Tetrabenazine, determined in an outward-facing conformation Descriptor: (3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one, Synaptic vesicular amine transporter Authors: Qu, Q, Wang, Y, Zhou, Z. Deposit date: 2023-09-30 Release date: 2024-06-12 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.37 Å) Cite: Transport and inhibition mechanism for VMAT2-mediated synaptic vesicle loading of monoamines. Cell Res., 34, 2024
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2023-09-30
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